High Content Screens & Target Identification
High content screening (HCS) combines the efficiency of high throughput techniques with the advantages of visual representation of entire cells and organisms. In contrast to classical high throughput screening methods that address only single enzymatic reactions or cellular properties, HCS allows quantitative analysis of multiparametric data derived from complex biological systems. This systemic pharmacological approach is particularly successful when screening small specialized compound libraries as it samples the entity of all cellular or organismic events and targets.